Key Finding: Losing and gaining weight can mess up your immune cells in your fat tissue, making you more likely to get sick or diabetic. ๐ฎ A new study used a cool technique to find this out.
Did you know that losing weight and gaining it back can make your immune system worse? ๐ฑ Yes! A new study published in The Nature Communications journal has revealed some shocking findings about how weight cycling affects the immune cells in your fat tissue. These cells are important for keeping your body healthy and preventing diseases like diabetes and cancer. Sounds crazy, right? ๐ฎ
The researchers used a special technique called CITEseq to analyze the immune cells in mice that were fed a high fat diet, a low fat diet, or a combination of both. They found that obesity changed the immune cells in a way that made them more inflammatory and less regulatory. This means they were more likely to cause damage and less likely to repair it.๐ข
But whatโs even more surprising is that these changes persisted even after the mice lost weight on a low fat diet. And when the mice regained weight on a high fat diet, the immune cells became even worse. They showed signs of exhaustion, activation, and enhanced lipid handling. This means they were less able to fight infections, more likely to trigger unwanted responses, and more prone to store fat.๐ฑ
The researchers concluded that weight cycling can have long-lasting effects on the immune cells in your fat tissue, which can lead to metabolic diseases like diabetes. So, what does this mean for you? ๐ค Well, it’s crucial to understand that this study was done on mice, so we can’t say for sure if the same thing happens in humans.
But as a weight loss coach, I think this study is very important and relevant for anyone who struggles with their weight. It shows that losing weight and keeping it off is not only good for your appearance, but also for your immune system and your health.๐
Now, before I conclude this story, tell me ๐ฌ, do you believe this study on mice could have implications for humans as well? What do you think? Iโd love to hear from you!๐